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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: Single-cell RNA sequencing reveals compartmental remodeling of tumor-infiltrating immune cells induced by anti-CD47 targeting in pancreatic cancer

Fig. 5

Anti-CD47 treatment remodels intratumoral monocyte/macrophage cells. a tSNE plot from merged data of intratumoral monocyte/macrophage cells. b tSNE plots with annotated clusters of intratumoral monocyte/macrophage cells. c tSNE plot of monocyte/macrophage cells displaying Nos2 and Mrc1 expression. d Heatmap from scRNA-seq displaying expression of select genes in each monocyte/macrophage cell subpopulation. e Heatmap of KEGG identifying pathway enrichment by each subpopulation. f tSNE plot with analysis of monocyte/macrophage cells by Monocle2. g Monocyte/macrophage subpopulations overlaid on Monocle2 pseudotime plot

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Journal of Hematology & Oncology

ISSN: 1756-8722

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