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Fig. 3 | Journal of Hematology & Oncology

Fig. 3

From: Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway

Fig. 3

ASPH-SRC signal promotes invadopodia formation, maturation, and function in pancreatic cancer. a Invadopodia formation and ECM degradation/remodeling in response to Wiskostatin. b 3-D tumor spheroid invasion in response to Wiskostatin. c 3-D pancreatosphere formation in response to Wiskostatin. d Transendothelial migration and extravasation. e Invasion through basement membrane and subsequent pancreatosphere formation in response to Wiskostatin. *p < 0.05; **p < 0.01; ***p < 0.001

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Journal of Hematology & Oncology

ISSN: 1756-8722

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