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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: Aspartate β-hydroxylase promotes pancreatic ductal adenocarcinoma metastasis through activation of SRC signaling pathway

Fig. 5

Expression profiling of ASPH network components in pancreatic cancer patients. a–f Expression of ASPH in a normal pancreas; b precursor lesions for sporadic pancreatic cancer: PanINs, IPMN, and MCN; c pancreatic MCAC; d invasive PDAC; e OGCs; f adjacent non-malignant pancreas. g, h Histopathologic characteristics and ASPH network expression profiling in two representative tumors derived from PDAC patients. SRC cascades were consistently g downregulated/silenced vs. h upregulated/activated in ASPH negative (patient #12) vs. positive (patient #13) PDAC

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Journal of Hematology & Oncology

ISSN: 1756-8722

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