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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

Fig. 1

Highly expressed LINC00958 is associated with clinicopathological characteristics and independently predicts overall survival. a Expression levels of LINC00958 in normal human liver cell line QSG-7701 and six HCC cell lines (Hep3B, Hep2, Huh7, MHCC-97H, Focus, and HCCLM3) were examined using RT-qPCR. b The expression levels of LINC00958 in 80 paired HCC tissues and non-tumor specimens were determined using RT-qPCR. c LINC00958 expression levels were detected in patients with well tumor differentiation and those with moderate/poor differentiation (n = 80). d Expression levels of LINC00958 were compared between patients without microvascular invasion (MVI) and those with MVI (n = 80). e LINC00958 expression levels were assessed in the TNM stage I/II group and the TNM III/IV group (n = 80). f FISH was used to determine the expression of LINC00958 in HCC tissue and the paired non-tumor sample. Statistical data are shown. g Kaplan-Meier survival curves showing the effect of LINC00958 on overall survival (P = 0.003) (n = 80). h Multivariate analyses of the independent predictive factors for overall survival. Hazard ratio (HR) and the corresponding 95% confidence interval (CI) are shown. *P < 0.05, **P < 0.01, ***P < 0.001

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