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Fig. 6 | Journal of Hematology & Oncology

Fig. 6

From: M6A-mediated upregulation of LINC00958 increases lipogenesis and acts as a nanotherapeutic target in hepatocellular carcinoma

Fig. 6

LINC00958 facilitates HCC growth in vivo. a A graphic illustration of the construction of HCC PDX mouse models. b The donor patients were clinically characterized. c The engrafted tumors were histopathologically analyzed. d The engrafted tumors in the sh-NC, sh-LINC00958, LINC00958, NC groups were harvested. e Tumor weight was recorded in the engrafted tumors. f Tumor volume was measured in the engrafted tumors. g FISH results showing the expression levels of LINC00958 in the engrafted tumors. h The expression level of LINC00958 was examined in the engrafted tumors by RT-qPCR. i The expression level of HDGF was assessed in the engrafted tumors by RT-qPCR. j The expression levels of HDGF, SERBP1, and Ki67 were determined in PDX tumor tissues using immunohistochemistry. ***P < 0.001

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