Fig. 4

AGK significantly enhances cell migration and invasion in RCC. a Wound-healing assays showing the migration of the indicated RCC cells. b Transwell analysis showing the invasion of the indicated RCC cells. c Statistical analysis of the number of cells that passed through the chamber. d Representative images of lungs with metastatic nodules and H&E staining of lung metastatic tumours in the tested mice. e Statistical analysis of the number of metastatic nodules formed in the lungs of mice. *P <  0.05; **P <  0.01