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Table 2 Univariate and multivariate Cox regression analysis of patient characteristics for overall survival and distant metastasis free survival among the 120 RCC patients

From: Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma

Covariant OS DMFS
HR (95% CI) P HR (95% CI) P
Univariate analysis
Gender (Female vs. Male) 0.581 (0.255–1.326) 0.197 0.641 (0.297–1.381) 0.256
Age (≤ 50 vs. > 50) 1.918 (0.789–4.663) 0.151 2.060 (0.901–4.707) 0.087
Family history of cancer (Y vs. N) 1.041 (0.244–4.442) 0.956 0.845 (0.200–3.566) 0.818
Clinical stage (I-II vs. III-IV) 34.361 (8.021–67.199) < 0.001 19.200 (6.601–55.842) < 0.001
Pathological classification (R vs. O) 1.232 (0.166–9.145) 0.838 1.211 (0.164–8.928) 0.851
Fuhrman classification (I-II vs. III-IV) 4.601 (2.023–10.464) < 0.001 4.835 (2.265–10.318) < 0.001
AGK expression (Low vs. High) 14.518 (3.369–62.556) < 0.001 11.028 (3.285–37.021) < 0.001
Multivariate analysis
Clinical stage (I-II vs. III-IV) 22.264 (4.944–50.248) < 0.001 11.727 (3.804–36.151) < 0.001
Fuhrman classification (I-II vs. III-IV) 1.125 (0.483–2.620) 0.785 1.428 (0.648–3.146) 0.376
AGK expression (Low vs. High) 7.492 (1.701–32.998) 0.008 6.161 (1.801–21.070) 0.004