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Table 2 Univariate and multivariate Cox regression analysis of patient characteristics for overall survival and distant metastasis free survival among the 120 RCC patients

From: Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma

Covariant

OS

DMFS

HR (95% CI)

P

HR (95% CI)

P

Univariate analysis

Gender (Female vs. Male)

0.581 (0.255–1.326)

0.197

0.641 (0.297–1.381)

0.256

Age (≤ 50 vs. > 50)

1.918 (0.789–4.663)

0.151

2.060 (0.901–4.707)

0.087

Family history of cancer (Y vs. N)

1.041 (0.244–4.442)

0.956

0.845 (0.200–3.566)

0.818

Clinical stage (I-II vs. III-IV)

34.361 (8.021–67.199)

< 0.001

19.200 (6.601–55.842)

< 0.001

Pathological classification (R vs. O)

1.232 (0.166–9.145)

0.838

1.211 (0.164–8.928)

0.851

Fuhrman classification (I-II vs. III-IV)

4.601 (2.023–10.464)

< 0.001

4.835 (2.265–10.318)

< 0.001

AGK expression (Low vs. High)

14.518 (3.369–62.556)

< 0.001

11.028 (3.285–37.021)

< 0.001

Multivariate analysis

Clinical stage (I-II vs. III-IV)

22.264 (4.944–50.248)

< 0.001

11.727 (3.804–36.151)

< 0.001

Fuhrman classification (I-II vs. III-IV)

1.125 (0.483–2.620)

0.785

1.428 (0.648–3.146)

0.376

AGK expression (Low vs. High)

7.492 (1.701–32.998)

0.008

6.161 (1.801–21.070)

0.004