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Table 2 Univariate and multivariate Cox regression analysis of patient characteristics for overall survival and distant metastasis free survival among the 120 RCC patients

From: Acylglycerol kinase promotes tumour growth and metastasis via activating the PI3K/AKT/GSK3β signalling pathway in renal cell carcinoma

CovariantOSDMFS
HR (95% CI)PHR (95% CI)P
Univariate analysis
Gender (Female vs. Male)0.581 (0.255–1.326)0.1970.641 (0.297–1.381)0.256
Age (≤ 50 vs. > 50)1.918 (0.789–4.663)0.1512.060 (0.901–4.707)0.087
Family history of cancer (Y vs. N)1.041 (0.244–4.442)0.9560.845 (0.200–3.566)0.818
Clinical stage (I-II vs. III-IV)34.361 (8.021–67.199)< 0.00119.200 (6.601–55.842)< 0.001
Pathological classification (R vs. O)1.232 (0.166–9.145)0.8381.211 (0.164–8.928)0.851
Fuhrman classification (I-II vs. III-IV)4.601 (2.023–10.464)< 0.0014.835 (2.265–10.318)< 0.001
AGK expression (Low vs. High)14.518 (3.369–62.556)< 0.00111.028 (3.285–37.021)< 0.001
Multivariate analysis
Clinical stage (I-II vs. III-IV)22.264 (4.944–50.248)< 0.00111.727 (3.804–36.151)< 0.001
Fuhrman classification (I-II vs. III-IV)1.125 (0.483–2.620)0.7851.428 (0.648–3.146)0.376
AGK expression (Low vs. High)7.492 (1.701–32.998)0.0086.161 (1.801–21.070)0.004