Fig. 5
From: MiR-612 regulates invadopodia of hepatocellular carcinoma by HADHA-mediated lipid reprogramming
HADHA promotes metastasis of HCC in vivo. a Metastatic foci in lung were imaged by micro-spiral CT scans using 3D synthesis. b, c Metastatic foci in lung and their statistic results of indicated HCCLM3 orthotopic xenografts (HCCLM3hadha-KD or HCCLM3NC) in H-E staining. d, e Metastatic foci in liver and their statistic results of indicated HCCLM3 orthotopic xenografts in H-E staining. Bars: (left) magnification × 100, scale bars, 200 μm. (right) magnification × 200, scale bars, 100 μm. f, g The levels of Cortactin and Caveolin-1 in liver orthotopic xenografts using IHC analyses. Bars: (up) magnification× 100, scale bars, 200 μm. (down) magnification × 200. scale bars, 100 μm. (*p < 0.05; **p < 0.01)