Fig. 2

LINC01234 promote NSCLC cells metastasis in vitro and in vivo. a–c Transwell assays of LINC01234-depleted (a, b) and LINC01234-overexpressing (c) NSCLC cells. d, e Experimental nude mouse model of metastasis of SPC-A1 and A549 cells stably transfected with LINC01234. Representative images of mouse lungs and number of visible tumor nodules on lung surfaces. Representative images of lungs and H&E-stained lung sections. f Western blot analysis of E-cadherin, N-cadherin, and Vimentin expression in NSCLC cells transfected with LINC01234 siRNAs. g Immunofluorescence analysis of E-cadherin in NSCLC cells depleted of LINC01234. *P < 0.05, **P < 0.01