Fig. 5

miR-27b-3p, miR-340-5p and VAV3 were participated in NSCLC cells metastasis. a Relative expression of miR-340-5p and miR-27b-3p in NSCLC cells transfected with miR-340-5p and miR-27b-3p mimics or inhibitors. b Transwell assays of the proliferative and invasive capacity of A549 and SPC-A1 cells overexpressing miR-340-5p or miR-27b-3p. c Transwell assays of SPC-A1 cells co-transfected with si-LINC01234, miR-340-5p inhibitors, or miR-27b-3p inhibitors. d qRT-PCR of VAV3 mRNA levels in NSCLC cells transfected with VAV3 siRNA. e Transwell assays of VAV3-depleted A549 and SPC-A1 cells. f Transwell assays of NSCLC cells expressing miR-340-5p or miR-27b-3p inhibitors, and partial rescue by VAV3 inhibition. g VAV3 protein levels in NSCLC cells co-transfected with VAV3 siRNA and miR-340-5p or miR-27b-3p inhibitors. *P < 0.05, **P < 0.01