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Fig. 7 | Journal of Hematology & Oncology

Fig. 7

From: Up-regulated LINC01234 promotes non-small-cell lung cancer cell metastasis by activating VAV3 and repressing BTG2 expression

Fig. 7

BTG2 has tumor suppressor functions in NSCLC cells. a qRT-PCR analysis of BTG2 mRNA levels in A549 and SPC-A1 cells overexpressing or depleted of BTG2. b Transwell assay of NSCLC cells overexpressing BTG2. c Western blot analysis of BTG2, E-cadherin and Vimentin protein levels after overexpression of BTG2. d Transwell assay of A549 and SPC-A1 cells overexpressing or depleted of LINC01234 and BTG2. e BTG2, E-cadherin and Vimentin protein levels were detected after co-transfection of cells with si-BTG2 and si-LINC01234 (left). BTG2, E-cadherin and Vimentin protein levels were detected after co-transfection of cells with BTG2 vector and LINC01234 vector (right). f Summary of the mechanism of LINC01234 in NSCLC cells. *P < 0.05, **P < 0.01

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