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Table 2 The miRNA regulating NKG2D ligands

From: The role of cancer-derived microRNAs in cancer immune escape

The targets of miRNAs miRNAs Cancer cell types Ref.
MICA miR-20a Ovarian cancer [74]
Hepatocellular carcinoma [75, 76]
Breast cancer [77]
Colorectal cancer [78]
Gastric cancer [79]
miR-93 Hepatocellular carcinoma [76, 80]
miR-106b Hepatocellular carcinoma [76, 80]
miR-106a Hepatocellular carcinoma [75]
miR-519a-3p Breast cancer [81]
miR-125ba Multiple myeloma [82]
miR-373 Hepatocellular carcinoma [75]
miR-302c Multiple cancers [83]
miR-520c Multiple cancers [83]
miR-153b Pancreatic cancer [84]
MICB miR-20a Breast cancer [77]
Hepatocellular carcinoma [75]
miR-373 Hepatocellular carcinoma [75]
miR-29a/b/c Hepatocellular carcinoma [75]
miR-15b Hepatocellular carcinoma [75]
miR-195 Hepatocellular carcinoma [75]
miR-16 Hepatocellular carcinoma [75]
miR-424 Hepatocellular carcinoma [75]
miR-106a Hepatocellular carcinoma [75]
miR-107 Hepatocellular carcinoma [75]
miR-17 Hepatocellular carcinoma [75]
miR-302c Multiple cancers [83]
miR-520c Multiple cancers [83]
ULBP miR-20a Breast cancer [77]
miR-519a-3p Breast cancer [81]
miR-302c Multiple cancers [83]
miR-520c Multiple cancers [83]
  1. MICA/B MHC-I chain-related molecules A/B (MICA/B), ULBP UL16-binding protein
  2. amiR-125b upregulates MICA via targeting the transcriptional suppressor of MICA
  3. bmiR-153 promotes the formation of sMICA by targeting HIF1A pathway