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Fig. 4 | Journal of Hematology & Oncology

Fig. 4

From: An Auristatin nanoconjugate targeting CXCR4+ leukemic cells blocks acute myeloid leukemia dissemination

Fig. 4

Follow-up of bioluminescence, detection of CD45 and CXCR4 expression in the disseminated AML mouse model. a Evolution of bioluminescence along 14 days period after the intravenous (i.v.) injection of CXCR4+ luciferase-transfected THP-1 cells (THP-1-Luci) in NSG mice measuring radiance intensity using the IVIS Spectrum. b Detection of CD45 and CXCR4 levels, by IHC, in the bone marrow, liver, and spleen of the leukemic mice 14 days after i.v. injection of THP-1-Luci cells

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