Fig. 3

Peripheral blood T cell receptor repertoire associated with overall survival. Correlation of B-Shannon (a, d), B-evenness (b, e), and B-clonality (c, f) of TCR CDR3s with the overall survival from advanced diagnoses. Spearman’s rank test was used to estimate correlations between the TCR repertoire indexes and overall survival (a, b, c). Kaplan-Meier analysis was used to estimate overall survival, presented as median values. The cut-off values of TCR repertoire indexes were determined by ROC analysis. The log-rank test was used to compare the curves (d, e, f). Abbreviations: mOS - median overall survival