Fig. 4

Abi1 deficiency abrogates the p185^Bcr-Abl-induced leukemogenesis in vivo. Survival of the syngeneic Balb/C mice injected with saline as a control (control) or 1X10⁶ of p185^Bcr-Abl Cas9 (p185 Cas9), p185^Bcr-Abl KO2.3 (p185 KO2.3), and p185^Bcr-Abl KO6.2 (p185 KO6.2) cells, as indicated. Survival of the mice were monitored and represented as the percentage of survival