Fig. 6

Expression of Oct4, M-CSF, and CD206 is positively correlated with each other in clinical lung tumor tissues. a Representative immunohistochemical staining of Oct4, M-CSF, and CD206 (M2 macrophage marker) in tumor tissues of patients with stages IB, IIB, and IIIA lung cancer and in normal tissues (× 200 magnification, scale bar = 100 μm). Negative control slides stained with isotype control IgG. b-d Immunoreactive intensities of Oct4, M-CSF, and CD206 were quantified, and the correlations between the levels of M-CSF and CD206 (n = 15) (b), Oct4 and CD206 (n = 22) (c), and Oct4 and M-CSF (n = 17) (d) were determined by Pearson's correlation coefficient. Scale bar, 100 μm