Fig. 1From: Biomarker-driven management strategies for peripheral T cell lymphomaBiomarker-driven strategies in peripheral T cell lymphoma. Positive and inhibitory interactions are depicted as solid arrows and bar-headed lines, respectively. The protein symbols of genes appear inside colored ovals. ALK, oncogenically activated anaplastic lymphoma kinase. AKT, protein kinase B. CCR4, chemokine receptor 4. CD30, cluster of differentiation 30. CD52, cluster of differentiation 52. CRBN, cereblon. DNMT, DNA methyltransferase. HDAC, histone deacetylase. ICOS, inducible T cell co-stimulator. mTOR, mammalian target of rapamycin. PD-1, programmed death receptor 1. PI3K, phophoinositide 3-kinase. TCR, T cell receptorBack to article page