Table 3 Univariable and multivariable analyses for overall survival

 Age at transplant

1.00 (0.99–1.02)

0.68

 Histology subtypes

AITL

1.00

0.30

ALCL*

1.03 (0.56–1.92)

ATLL

1.62 (0.77–3.43)

NOS

0.79 (0.48–1.3)

NK/T nasal

1.93 (0.92–4.07)

HSTL

0.79 (0.24–2.6)

Other subtypes

1.32 (0.32–5.54)

 Time from diagnostic to alloSCT > 12 months

0.9 (0.6–1.33)

0.59

 Number of lines of treatment ≤ 2

0.71 (0.47–1.08)

0.11

 Karnofsky score at transplant (%)

100

1.00

0.001

80–90

2.08 (1.27–3.4)

< 80

4.00 (1.7–9.41)

 Disease status at transplant

CR

1.00

0.011

PR

0.83 (0.51–1.37)

PD

2.13 (1.27–3.57)

 HLA-matched donor

0.71 (0.45–1.12)

0.16

 Conditioning regimen

MAC

1.00

0.86

RIC

0.96 (0.64–1.45)

 CMV status (D/R)

Neg/neg

1.00

0.89

Others

0.97 (0.63–1.49)

 Mismatch sex (F/H vs others)

1.39 (0.91–2.12)

0.14

 Source of stem cells

BM

1.00

0.022

Cord blood

1.44 (0.76–2.73)

PBSC

0.69 (0.41–1.14)

 Acute GvHD (grades 3–4)

2.69 (1.67–4.33)

0.0002

 Chronic GvHD

1.22 (0.72–2.06)

0.47

HR (95% CI)

p value

 Acute GvHD (grade 3-4)

2.57 (1.53–4.31)

0.00036

 Karnofsky score (%)

90–80 vs 100

2.07 (1.24–3.44)

0.0053

< 80 vs 100

5.14 (2.02–13.06)

0.00058

 Disease status before transplant

PR vs CR

0.72 (0.42–1.24)

0.24

PD vs CR

2.21 (1.25–3.89)

0.0062

 Stem cell source

Cord blood vs BM

1.78 (0.90–3.51)

0.10

PBSC vs BM

0.85 (0.50–1.45)

0.54