Fig. 3
From: Emerging role of RNA methyltransferase METTL3 in gastrointestinal cancer
The biological function of METTL3 in gastrointestinal cancer. METTL3 regulates the differential expression of oncogenes and tumor suppressor genes at posttranscriptional levels by mediating RNA stability and translation, which contributes to processes involved in the development of gastrointestinal cancer, including cell proliferation, apoptosis, invasion, migration, metastasis, angiogenesis, radiochemotherapy resistance, glycolysis/lipid metabolism, and CSC maintenance in gastrointestinal cancer