Fig. 4

Kaplan–Meier estimates of PFS by COO status by treatment group. a Investigator-assessed PFS by COO with G-CHOP, where GCB appeared to have a better outcome compared with ABC and unclassified subgroups. b Investigator-assessed PFS by COO with R-CHOP, where GCB also appeared to have a better outcome versus ABC and unclassified subgroups. ABC, activated B cell; COO, cell of origin; GCB, germinal center B cell; G-CHOP, obinutuzumab plus cyclophosphamide, doxorubicin, vincristine, and prednisone; PFS, progression-free survival; OS, overall survival; R-CHOP, rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone