Fig. 2From: Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapyIGF and insulin signaling pathways. IGF and insulin can activate multiple signaling pathways including PI3K, MAPK, JAK/STAT, discoidin domain receptors (DDRs), FAK, and Src; promote cell proliferation, survival, epithelial-mesenchymal transition (EMT), migration, and stemness; and inhibit autophagy and anoikisBack to article page