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Table 3 The DALY of AML in 1990/2017 and temporal trends

From: The global burden and attributable risk factor analysis of acute myeloid leukemia in 195 countries and territories from 1990 to 2017: estimates based on the global burden of disease study 2017

 

1990

2017

1990–2017

DALY

No *103 (95% CI)

Age-standardized DALY rate/100,000

No. (95% CI)

DALY

No *103 (95% CI)

Age-standardized DALY rate/100,000

No. (95% CI)

EAPC

No. (95% CI)

Overall

2063.15 (1709.81~2905.02)

40.44 (34.40~54.66)

3221.47 (2890.15~3438.43)

41.67 (37.33~44.54)

0.13 (0.07~0.18)

Sex

Male

1088.68 (933.08~1391.83)

43.73 (38.41~53.39)

1868.89 (1585.26~2016.44)

49.20 (41.72~53.11)

0.46 (0.41~0.51)

Female

974.48 (746.51~1580.45)

37.59 (29.52~59.04)

1352.58 (1179.10~1523.70)

34.54 (30.02~39.09)

− 0.31 (− 0.37~− 0.24)

Socio-demographic factor

High SDI

610.21 (593.61~628.16)

56.05 (54.22~57.91)

861.46 (826.28~888.95)

51.97 (49.74~53.94)

− 0.20 (− 0.34~− 0.06)

High-middle SDI

447.39 (390.99~561.34)

40.80 (35.79~51.00)

515.17 (458.32~545.11)

34.99 (31.06~37.15)

− 0.55 (− 0.62~− 0.49)

Middle SDI

419.96 (338.90~589.84)

28.15 (23.30~38.17)

704.89 (616.44~764.59)

33.32 (29.19~36.24)

0.61 (0.58~0.65)

Low-middle SDI

329.85 (230.63~545.05)

32.91 (24.57~50.01)

650.74 (568.11~755.33)

40.40 (35.56~47.05)

0.74 (0.69~0.79)

Low SDI

250.16 (133.49~575.40)

37.25 (23.51~72.49)

482.40 (384.94~561.43)

41.21 (33.14~46.98)

0.30 (0.26~0.33)

Region

Andean Latin America

11.75 (8.62~16.79)

31.52 (24.54~42.87)

26.54 (19.08~31.12)

44.19 (31.90~51.59)

1.59 (1.46~1.73)

Australasia

17.46 (16.64~18.20)

78.76 (74.99~82.18)

23.80 (21.54~26.17)

62.73 (56.85~69.03)

− 1.18 (− 1.37~− 0.98)

Caribbean

15.52 (12.25~24.46)

45.23 (36.60~68.30)

20.14 (17.34~24.90)

42.78 (36.63~53.61)

− 0.12 (− 0.28~0.04)

Central Asia

30.95 (26.26~37.11)

44.07 (38.45~52.24)

40.44 (36.85~44.28)

44.91 (40.95~49.13)

0.38 (0.25~0.51)

Central Europe

68.30 (63.12~74.47)

51.31 (46.80~56.44)

83.31 (76.99~87.51)

52.34 (48.18~55.40)

0.39 (0.27~0.51)

Central Latin America

63.33 (60.51~72.47)

39.86 (38.41~44.41)

112.92 (106.23~118.37)

44.64 (41.90~46.78)

0.41 (0.32~0.50)

Central sub-Saharan Africa

20.60 (11.43~45.70)

39.92 (25.87~64.43)

44.34 (31.22~66.31)

41.07 (28.80~50.97)

− 0.01 (− 0.14~0.12)

East Asia

255.31 (182.27~403.90)

20.44 (14.74~31.95)

287.95 (237.67~325.95)

19.47 (16.08~22.07)

− 0.39 (− 0.55~− 0.24)

Eastern Europe

125.38 (103.21~134.11)

54.04 (44.37~58.01)

100.72 (93.99~107.63)

40.05 (36.99~43.33)

− 1.3 (− 1.44~− 1.16)

Eastern sub-Saharan Africa

62.39 (37.66~110.88)

35.26 (24.60~54.37)

151.95 (110.81~187.83)

43.83 (33.07~52.92)

0.72 (0.62~0.82)

High-income Asia Pacific

102.63 (98.18~106.74)

56.08 (53.16~58.77)

116.96 (109.06~124.24)

41.07 (37.61~44.39)

− 0.96 (− 1.13~− 0.80)

High-income North America

183.11 (79.19~188.19)

58.14 (56.87~59.63)

284.65 (273.72~296.64)

57.13 (54.81~59.92)

− 0.1 (− 0.29~0.08)

North Africa and Middle East

158.77 (103.98~269.53)

49.15 (32.55~77.32)

240.16 (200.29~292.56)

42.22 (35.14~51.02)

− 0.38 (− 0.49~− 0.26)

Oceania

3.52 (2.50~5.64)

57.85 (42.37~85.48)

7.00 (5.11~10.58)

58.37 (43.45~84.18)

0.15 (0.07~0.23)

South Asia

369.72 (235.28~688.01)

35.87 (25.05~59.11)

705.85 (611.78~813.39)

42.6 (37.00~48.84)

0.59 (0.51~0.66)

Southeast Asia

133.06 (89.81~238.42)

31.44 (22.75~52.67)

261.12 (222.66~306.94)

40.17 (34.35~47.00)

1.05 (0.93~1.16)

Southern Latin America

23.26 (21.47~25.14)

47.14 (43.50~50.96)

31.77 (28.93~34.56)

45.14 (41.04~49.30)

− 0.13 (− 0.24~− 0.01)

Southern sub-Saharan Africa

20.25 (14.92~23.42)

44.10 (32.64~51.71)

32.29 (23.32~38.31)

44.59 (32.55~52.50)

− 0.21 (− 0.55~0.14)

Tropical Latin America

76.82 (71.52~81.77)

52.92 (49.84~55.71)

113.41 (106.70~118.33)

50.65 (47.54~53.23)

− 0.12 (− 0.22~− 0.02)

Western Europe

254.91 (246.17~265.24)

54.79 (52.76~57.05)

365.39 (343.08~386.36)

54.91 (51.16~58.51)

0.13 (− 0.06~0.32)

Western sub-Saharan Africa

66.12 (41.01~101.06)

32.44 (22.56~43.65)

170.78 (117.14~208.56)

37.83 (26.76~46.50)

0.47 (0.34~0.60)

  1. DALY disability-adjusted life years