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Table 3 Clinical trials of CAR NK cell therapies around the world

From: Recent advances in CAR-T cell engineering

Number Disease Binding epitope Location Start time Study completion Number enrolled Status
NCT03692767 B cell lymphoma CD19 NA 2019/3/1 2021/11/1 9 Not yet recruiting
NCT03690310 B cell lymphoma CD22 NA 2019/3/1 2021/11/1 9 Not yet recruiting
NCT03824964 B cell lymphoma CD19/CD22 NA 2019/2/1 2021/1/1 10 Not yet recruiting
NCT03056339 B lymphoid malignancies CD19 Texas, USA 2017/6/21 2022/6/1 36 Recruiting
NCT03692663 Prostate cancer PSMA NA 2018/12/1 2021/12/1 9 Not yet recruiting
NCT03692637 Epithelial ovarian cancer Mesothelin NA 2019/3/1 2021/11/1 30 Not yet recruiting
NCT03383978 Glioblastoma HER2 Frankfurt, Germany 2017/12/1 2020/8/1 30 Recruiting
NCT03940833 Multiple myeloma BCMA Jiangsu, China 2019/5/1 2022/5/1 20 Recruiting
NCT04004637 NK/T cell lymphoma, ALL CD7 Henan, China 2019/6/1 2021/6/1 10 Recruiting
NCT03941457 Pancreatic cancer ROBO1 Shanghai, China 2019/5/1 2022/5/1 9 Recruiting
NCT03940820 Solid tumor ROBO1 Jiangsu, China 2019/5/1 2022/5/1 20 Recruiting
NCT03415100 Solid tumors NKG2DL Guangdong, China 2018/1/2 2019/12/1 30 Recruiting