Table 2 Stimulatory immune checkpoint-like effects of VISTA
From: VISTA: an immune regulatory protein checking tumor and immune cells in cancer immunotherapy
Cancer type | Research object | VISTA expression | Reference |
|---|---|---|---|
Ovarian cancer | Samples from patients with stage I–IV ovarian cancer | Tumor cells, immune cells, endothelial cells | Zong et al. [41] |
Esophageal adenocarcinoma | Patient samples | Tumor cells; CD68+ TILs, CD4+ TILs | Loeser et al. [46] |
Gastric cancer | Samples from patients with gastric cancer and corresponding liver metastases | Tumor cells, immune cells, endothelial cells | Boger et al. [45] |
Hepatocellular carcinoma | Patient samples | Tumor cells, immune cells | Zhang et al. [47] |