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Table 2 Evaluation of the 7-AAb panel in AFP HCC detection

From: Autoantibody signature in hepatocellular carcinoma using seromics

Phase AFP HCC vs. (healthy + cirrhotic) AFP HCC vs. healthy AFP HCC vs. cirrhotic
AUC Specificity Sensitivity AUC Specificity Sensitivity AUC Specificity Sensitivity
Test phase (II) 0.898 89.4% 70.4% 0.937 88.9% 83.5% 0.841 87.0% 64.3%
Validation phase (III) 0.926 90.1% 80.6% 0.948 93.4% 83.7% 0.886 85.2% 77.5%
Test phase (II) + validation phase (III) 0.912 89.1% 76.1% 0.942 93.4% 80.3% 0.862 89.6% 65.7%