Fig. 3From: High mobility group box 1 (HMGB1): a pivotal regulator of hematopoietic malignanciesThe roles of HMGB1 and associated molecules in BM. HMGB1 binds with a series of receptors or interactors and plays important roles in enhancing HSC self-renewal and differentiation, promoting senescence, regulating genomic instability, regulating hematopoiesis, mediating immunity, and affecting the inflammatory BM microenvironmentBack to article page