Fig. 1

High CDK7 expression is associated with poor prognosis in NSCLC. a Kaplan-Meier survival curves (K-M curve) showing the relationship between CDK7 mRNA level and OS in the TCGA LUAD data by GraphPad Prism Software (n = 526) (P = 0.0412). b K-M curve showing the relationship between CDK7 mRNA level and OS in GSE37745 data (n = 196) (P = 0.0214). c K-M curve showing the relationship between CDK7 protein level and OS in cohort I from Shanghai Outdo Biotech (n = 92) (P = 0.0358). d K-M curve showing the relationship between CDK7 protein level and OS in cohort II from Tongji Hospital (n = 222) (P = 0.0031). e Data mining showing differential CDK7 mRNA levels in adjacent and tumor tissue in TCGA LUAD data (P < 0.001). f The CDK7 protein level in adjacent and tumor tissue in cohort I, as examined by immunohistochemistry (IHC) (P < 0.001). g Representative scanned images of tissue cores with low or high CDK7 by IHC. Left, original magnification, × 6; scale bar, 500 μm. Right, original magnification, × 400; scale bar, 50 μm