Fig. 7

In addition to producing protein-encoding mRNA, genomic DNA also produces many non-coding RNAs, including long non-coding RNA (lncRNA) and miRNA, many of which are directly involved in transcription control. The occurrence of RNA transcription regulation involves multiple RNA-binding proteins (SRSF2, RBFox2, NONO). The abnormal function of typical splicing regulators in transcription is closely related to the pathogenesis of cancer