Skip to main content
Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Role of CD47 in Hematological Malignancies

Fig. 2

Therapeutic approaches for targeting CD47 in hematological malignancies. Blockade of CD47-SIRPα interaction (blocking “don't eat me” signal) through different approaches including antibodies, recombinant peptide agonists, miRNAs, and QPCTL inhibitors enhances the activity of phagocytes toward tumor cells (activating “eat me” signal). Dual blockade of CD47 and other hematological surface markers by antibody therapies is another approach to synergistically target tumor cells

Back to article page