Fig. 7
Methylation-expression correlation the hyperdiploid subgroups. DNA-methylation level (horizontal; median values) at DMRs vs. expression (vertical; log2 values) of nearest genes were plotted for promoter and gene body in HRD-D1 (a) and HRD-D2 (b) subgroups. DMR methylation level vs. expression (based on correlation r2>0.2, excluding control) of selected biologically relevant MM GEMs were represented as heat maps for HRD-D1 (c) and HRD-D2 subgroups (d).