Fig. 8
Distribution of DNA methylation and histone modifications of CCND1 and CCND2 in NDMM. (a) Median DMR methylation level vs. expression correlated for CCND2 (r2=0.59), but not for CCND1 (r2=0.14) across the subgroups. DNA methylation levels across CCND1 (b) and CCND2 (c) for each subgroup. (d) Chromatin marks at CCND1 (d) and CCND2 (E) in three different cells lines representing the t(4;14), t(11;14) and t(14;16) subgroups.