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Fig. 1 | Journal of Hematology & Oncology

Fig. 1

From: Roles of METTL3 in cancer: mechanisms and therapeutic targeting

Fig. 1

m6A RNA methylation and the structure of METTL3, the catalytic subunit of the m6A methyltransferase complex. a The writers and erasers of the dynamic m6A modification. b Schematic domain structure of METTL3. c Structure of the zinc finger domain (ZFD) of METTL3 (PDB ID: 5yz9). d Structure of the methyltransferase domain (MT-A70) of METTL3 (PDB ID: 5l6d)

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