Fig. 4

Risk of 27 specific cancer types in the Copenhagen General Population Study according to HDL cholesterol and apolipoprotein A1 levels. Hazard ratios (HRs) and 95% confidence intervals (CIs) were obtained from Cox proportional hazards regression multivariable adjusted for age, sex, body mass index, smoking status, cumulative tobacco consumption, alcohol intake, leisure-time physical activity, education, income, plasma triglycerides, lipid-lowering therapy, C-reactive protein, and baseline chronic disease (ischemic heart disease, chronic obstructive pulmonary disease, and diabetes). Numbers vary slightly due to exclusion of individuals with baseline cancer for the relevant type of cancer. The sum of the 27 specific cancer types exceeds the number of any cancer, as some participants developed more than one type of cancer. HDL=high-density lipoprotein. *P value <0.05 after adjustment for 28 multiple comparisons according to the method of Bonferroni; P value=0.05 is equivalent to P=0.05/28=0.002