Skip to main content

Table 1 Timeline of events from initial COVID-19 diagnosis to second COVID-19 episode

From: Severe COVID-19 virus reactivation following treatment for B cell acute lymphoblastic leukemia

Date 4/8/20 4/25/20 5/7/20 5/11/20 5/14/20 6/8/20 6/18/20 6/25/20 6/28/20
SARS-CoV-2 PCR Positive Positive Negative Negative    Positive   Positive
COVID-19 antibodies   Positive (1:80)    Positive (1:960)    Negative  
COVID-19 symptoms   Fever, cough, abdominal pain, nausea, vomiting
No oxygen requirement
       Fever, acute respiratory distress requiring high-flow nasal cannula
White blood cell count (× 103/uL) 3.5 11.7 5.0    10.6 3.5 0.3 4.6
Absolute lymphocyte count (× 103/uL) 1.9 1.4 1.6    2.6 0.2 0.1 0.1
C-reactive protein (mg/L)   168.1 9.2       314.3
Erythrocyte sedimentation rate (mm/h)           > 145
Ferritin (ng/mL)   4569 3662        > 33,511
Interleukin 6 (pg/mL)   93.4        139.0
Fibrinogen (mg/dL)   603 567       710
D-dimer (μg/mL FEU)   0.83 0.39       3.54
CT chest findings   Moderate, bilateral, scattered ground-glass opacities        Extensive, diffuse ground-glass opacities including previously unaffected sites
Leukemia treatment       Rituximab
Cytarabine
Dasatinib