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Table 1 Summary of therapeutic antibodies combined with inhibition of autophagy

From: Targeting autophagy to overcome drug resistance: further developments

Therapeutic antibodies

Targets

Combination therapy

Indications

References

Rituximab

CD20

CQ

Non-Hodgkin lymphoma

[151]

Bevacizumab

VEGF

CQ

HCC

[152]

Cetuximab

EGFR

CQ

Vulvar squamous carcinoma

[147]

  

Overexpressed Bcl-2

Colorectal adenocarcinoma

 
  

siRNA ATG7

Lung adenocarcinoma

 
  

siRNA Beclin1

  

Gemtuzumab ozogamicin

CD33

PP242

Acute myeloid leukemia

[153]

  

AZD2014

 

[154]

DN30

Met

Baf

Cardiomyoblasts

[155]

DO24

    

Trastuzumab

HER2

CQ

Breast cancer

[148]

Milatuzumab

CD74

FTY720

Mantle cell lymphoma

[156]

Tositumomab

CD20

Overexpressed Bcl-2

B cell malignancies

[157]

  

siRNA Beclin1

  
  

siRNA ATG 12

  

CH12

EGFRvIII

siRNA ATG7

HCC

[158]

  

siRNA Beclin1

  

β2M mAb

β2-microglobulin

Bortezomib

Multiple myeloma

[159]

PD-1 mAb

PD-1

Pemetrexed + sildenafil

Non-small cell lung cancer

[160]

CTLA4 mAb

CTLA4

  Â