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Table 5 CircRNAs regulate UPR pathway components

From: Interplay between endoplasmic reticulum stress and non-coding RNAs in cancer

CircRNAs Expression level Tumor type UPR-related Mechanism Biological process References
Circ_002117 Downregulated Gastric cancer Increases expression of GRP78, IRE1, eIF2α, and CHOP Promotes apoptosis [148]
CircCDR1 Upregulated OSCC Increases eIF2α expression Inhibits apoptosis [149]
CircRNA_101036 Downregulated OSCC Increases CHOP and ROS levels Induces cell apoptosis [150]
  1. OSCC, oral squamous cell carcinoma