Table 5 CircRNAs regulate UPR pathway components
From: Interplay between endoplasmic reticulum stress and non-coding RNAs in cancer
CircRNAs | Expression level | Tumor type | UPR-related Mechanism | Biological process | References |
|---|---|---|---|---|---|
Circ_002117 | Downregulated | Gastric cancer | Increases expression of GRP78, IRE1, eIF2α, and CHOP | Promotes apoptosis | [148] |
CircCDR1 | Upregulated | OSCC | Increases eIF2α expression | Inhibits apoptosis | [149] |
CircRNA_101036 | Downregulated | OSCC | Increases CHOP and ROS levels | Induces cell apoptosis | [150] |