Fig. 5From: Abnormally activated OPN/integrin αVβ3/FAK signalling is responsible for EGFR-TKI resistance in EGFR mutant non-small-cell lung cancerThe FAK signalling pathway contributes to acquired resistance to osimertinib in NSCLC. a, b Western blot analysis was used to detect the effect of osimertinib treatment on p-FAK, p-AKT and p-ERK in PC9 cells at different concentrations and times. c, d Western blot analysis was used to detect the effect of osimertinib treatment on p-EGFR, p-FAK, p-AKT, and p-ERK in PC9GR and H1975 cells at different concentrationsBack to article page