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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: Abnormally activated OPN/integrin αVβ3/FAK signalling is responsible for EGFR-TKI resistance in EGFR mutant non-small-cell lung cancer

Fig. 5

The FAK signalling pathway contributes to acquired resistance to osimertinib in NSCLC. a, b Western blot analysis was used to detect the effect of osimertinib treatment on p-FAK, p-AKT and p-ERK in PC9 cells at different concentrations and times. c, d Western blot analysis was used to detect the effect of osimertinib treatment on p-EGFR, p-FAK, p-AKT, and p-ERK in PC9GR and H1975 cells at different concentrations

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