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Fig. 6 | Journal of Hematology & Oncology

Fig. 6

From: Proteomic signatures of 16 major types of human cancer reveal universal and cancer-type-specific proteins for the identification of potential therapeutic targets

Fig. 6

Characterization of cancer-related druggable proteins. a Drug types according to the DrugBank. These drugs had targets identified in our proteomic data. b Cellular localization of identified druggable proteins. c Some identified drug targets with corresponding drugs in this study. d A model depicts the CDK2 and CDK4/6 regulating proliferation and apoptosis of tumor cells through retinoblastoma protein (RB) phosphorylation. e Elevated expression of cancer/testis (CT) antigens in tumor tissues in at least one cancer type compared to normal tissues. f A model shows the MAGEA4 vaccine for the inhibition of tumor cell proliferation

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Journal of Hematology & Oncology

ISSN: 1756-8722

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