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Fig. 2 | Journal of Hematology & Oncology

Fig. 2

From: Identification of a small molecule as inducer of ferroptosis and apoptosis through ubiquitination of GPX4 in triple negative breast cancer cells

Fig. 2

The antiproliferative activity of DMOCPTL in TNBC cells. a The chemical structure of DMOCPTL. b The effect of DMOCPTL on the viability of MDA-MB-231 and SUM159 cells after being treated for 72 h. c The representative pictures and colony number of MDA-MB-231 and 4T1 cells after treatment of DMOCPTL at concentrations of 0.05 μM, 0.1 μM and 0.25 μM, respectively. d The effect of DMOCPTL and PTL at a concentration of 0.5 μM on colony formation in MDA-MB-231 cells. Analysis results represented mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001

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