Fig. 7
GPX4 was overexpressed in breast cancer. a The Functional state analysis of GPX4 in breast cancer cells in patient 1. b The expression distribution of GPX4 in breast cancer cells in CancerSEA database in patient 1. Every point represents a single cell. c The correlation of GPX4 with cell apoptosis was analyzed in patient 1. d The expression distribution of GPX4 in breast cancer cells in CancerSEA database in patient 2. Every point represents a single cell. e The Functional state analysis of GPX4 in breast cancer cells in patient 2. The correlation of GPX4 with hypoxia (f), invasion (g), cell cycle (h) and DNA damage (I) were investigated in breast cancer cells in CancerSEA database in patient 2. Every point represents a single cell. j IHC analysis of GPX4 expression in breast cancer tissue with different stages and normal breast tissue. k The statistical results of GPX4 expression in breast cancer tissue with different stages and normal breast tissue. l The IHC results of GPX4 expression in TNBC and non-TNBC breast cancer tissues. Analysis results represented mean ± SD, *P < 0.05, **P < 0.01, ***P < 0.001