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Fig. 5 | Journal of Hematology & Oncology

Fig. 5

From: HOMER3 facilitates growth factor-mediated β-Catenin tyrosine phosphorylation and activation to promote metastasis in triple negative breast cancer

Fig. 5

HOMER3 is essential for EGF-mediated aggressiveness in TNBC. a, b TNBC cells that had HOMER3 knockdown, or restoration of indicated HOMER3 truncated constructs, were treated with EGF, and subjected for transwell matrix penetration assays. Representative images (a) and quantification (b) of invading TNBC cells were shown. c 3-D spheroid cultured in matrigel was used to determine the invasive capacity of indicated cells. d Statistic analysis showed the percentage of colonies with invasive structures

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Journal of Hematology & Oncology

ISSN: 1756-8722

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