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Fig. 6 | Journal of Hematology & Oncology

Fig. 6

From: Targeting B7-H3 via chimeric antigen receptor T cells and bispecific killer cell engagers augments antitumor response of cytotoxic lymphocytes

Fig. 6

Dynamic caspase-3 activation in apoptotic cells in response to B7-H3/CD16 BiKE. a FRET imaging of A549-C3 cells live cells appeared in green color and apoptotic cells in blue color. A549-C3 cells were treated with B7-H3/CD16 BiKE (5 μg/mL) with PBMCs at E:T = 10 for 12,24, and 36 h. b Statistical analysis of apoptotic rate at different time points. Representative images are shown. Sample size: 1 × 105 target cells. The p values were analyzed using a Student’ t test

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