Fig. 3

CXCL12α and CXCL12γ induce MM cell adhesion to VCAM-1. a Adhesion of XG1, MM1.S, and L363 cells to a surface co-coated with either VCAM-1 and CXCL12α or CXCL12γ at indicated concentrations. Adhesion was allowed for 2 min, and adhesion in the absence of CXCL12 was normalized to one. The mean ± SD of at least three independent experiments in triplicate is shown. b Adhesion of XG1, MM1.S, and L363 cells to VCAM-1. CXCL12α or CXCL12γ at indicated concentrations (nM) was either co-coated with VCAM-1 (coated) or present in the medium in soluble form (soluble). Adhesion in the absence of CXCL12 was normalized to one. Mean ± SD of at least three independent experiments in triplicate is shown