|
Follow-up duration in m, median (range)
|
24.88 (12.13;46.05)
|
25.37 (13.21;42.56)
|
0.92
|
|
Age at transplant in years, median (range)
|
37.7 (18–76.1) [27–49.5]
|
37.1 (18.1–75) [25.7–51]
|
0.58
|
|
Year of transplant
|
2015 (2012–2018)
|
2016 (2012–2018)
|
< 0.0001
|
|
Patient gender, n (%)
| | | |
|
Male
|
1129 (59.8%)
|
268 (64.9%)
|
0.055
|
|
Female
|
759 (40.2%)
|
145 (35.1%)
| |
|
Diagnosis
| | | |
|
Ph-neg B ALL
|
616 (32.6%)
|
148 (35.8%)
|
0.44
|
|
Ph-pos B ALL
|
725 (38.3%)
|
151 (36.6%)
| |
|
T-ALL
|
550 (29.1%)
|
114 (27.6%)
| |
|
Patient CMV status
| | | |
|
Patient CMV negative, n (%)
|
521 (28.1%)
|
90 (22%)
|
0.01
|
|
Patient CMV positive, n (%)
|
1335 (71.9%)
|
319 (78%)
| |
|
Donor CMV status
| | | |
|
Donor CMV negative, n (%)
|
599 (33%)
|
110 (27.1%)
|
0.021
|
|
Donor CMV positive, n (%)
|
1215 (67%)
|
296 (72.9%)
| |
|
Status at transplant
| | | |
|
CR1
|
1575 (83.3%)
|
275 (66.6%)
|
< 0.0001
|
|
CR2
|
316 (16.7%)
|
138 (33.4%)
| |
|
KPS at transplant, n (%)
| | | |
|
< 90
|
397 (22.4%)
|
100 (25%)
|
0.27
|
|
≥ 90
|
1373 (77.6%)
|
300 (75%)
| |
|
Missing
|
121
|
13
| |
|
Donor age, y median (range)
|
38.5 (0.1–74) [27.5–50.5]
|
38.8 (7.8–74.3) [27.1–49.3]
|
0.79
|
|
Donor gender
| | | |
|
Male donor
|
1033 (54.9%)
|
242 (58.6%)
|
0.17
|
|
Female donor
|
848 (45.1%)
|
171 (41.4%)
| |
|
Donor-recipient gender matching, n (%)
| | | |
|
Female–male
|
474 (25.2%)
|
110 (26.6%)
|
0.54
|
|
Other
|
1408 (74.8%)
|
303 (73.4%)
| |
|
MRD at transplant
| | | |
|
Negative
|
681 (67.4%)
|
162 (65.3%)
|
0.54
|
|
Positive
|
330 (32.6%)
|
86 (34.7%)
| |
|
Missing
|
880
|
165
| |
