Fig. 2From: Bispecific T cell engagers: an emerging therapy for management of hematologic malignanciesMechanisms of tumor cell lysis mediated by the BiTEs. BiTEs can redirect T cells to tumor cells and active T cells. Activated T cells release perforin and other granzymes through immunological synapses. These cytolytic proteins can form endosomes in tumor cells and lyse tumor cells ultimatelyBack to article page