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Table 1 Burden of AYA cancers and percentage change in age-standardized rates from 1990 to 2019

From: The global, regional, and national burden of cancer among adolescents and young adults in 204 countries and territories, 1990–2019: a population-based study

  Incidence Deaths DALYs
  Number of incident cases, 2019 Age-standardized incidence rate (per 100,000 population), 2019 Percentage change in rates, 1990–2019 Number of deaths, 2019 Age-standardized death rate (per 100,000 population), 2019 Percentage change in rates, 1990–2019 Number of DALYs, 2019 Age-standardized DALYs rate (per 100,000 population), 2019 Percentage change in rates, 1990–2019
Global 1,194,382 39.7 10.7 396,117 13.2 − 21 23,491,284 782.3 − 20
Female 685,639 45.9 9.5 202,452 13.6 − 20.9 11,973,819 804.1 − 19.9
Male 508,743 33.5 12 193,665 12.8 − 21.2 11,517,464 760.4 − 20.2
High SDI 213,165 59.6 5.2 33,370 9.2 − 33.7 2,017,829 564.4 − 32
High-middle SDI 301,329 53.1 30.1 76,612 13.4 − 28.4 4,515,373 801.5 − 27
Middle SDI 355,636 36.9 16.5 131,819 13.7 − 25.4 7,783,143 810.2 − 24.1
Low-middle SDI 207,656 29.2 16.5 100,583 14.2 − 5.1 5,968,398 836.8 − 4.8
Low SDI 97,858 24.3 3.9 53,478 13.3 − 3.7 3,191,436 781.2 − 3.2
Acute lymphoid leukaemia 38,747 1.3 66.6 11,696 0.4 − 10.6 765,511 26.1 − 9.9
Acute myeloid leukaemia 20,183 0.7 5.6 12,166 0.4 − 0.1 747,561 25.2 − 0.2
Bladder cancer 14,095 0.5 29 2050 0.1 − 22.6 124,475 4.1 − 20.2
Brain and central nervous system cancer 61,511 2.1 23.9 29,105 1 − 6.9 1,746,906 58.4 − 6.6
Breast cancer 169,859 5.6 25.7 43,088 1.4 − 4.7 2,489,420 82.1 − 2.8
Cervical cancer 119,258 3.9 − 4.2 27,168 0.9 − 24.3 1,560,541 51.4 − 23.7
Chronic lymphoid leukaemia 4263 0.2 113.4 1010 0 1.7 61,375 2.6 4.3
Chronic myeloid leukaemia 9203 0.3 − 16 4956 0.2 − 33.1 294,861 9.8 − 33
Colon and rectum cancer 76,090 2.5 38.8 28,352 0.9 − 2.7 1,633,410 53.9 − 2.1
Esophageal cancer 8088 0.3 − 23.9 6215 0.3 − 29.7 343,752 14.5 − 29.4
Gallbladder and biliary tract cancer 3841 0.2 − 10.5 2390 0.1 − 17.1 132,562 5.6 − 17
Hodgkin lymphoma 33,388 1.1 − 8.6 8093 0.3 − 34.3 508,216 17.1 − 33.3
Kidney cancer 21,136 0.7 62.9 4017 0.1 20.7 239,153 7.9 22.1
Larynx cancer 4214 0.2 − 15.4 2250 0.1 − 29.3 128,189 5.4 − 28.7
Lip and oral cavity cancer 29,440 1 29.9 10,043 0.3 19.3 580,333 19.2 19.4
Liver cancer 25,430 0.8 − 50.9 18,573 0.6 − 57.5 1,046,876 34.6 − 57.1
Malignant skin melanoma 37,266 1.2 16.3 4248 0.1 − 23.9 259,089 8.6 − 21.6
Mesothelioma 1466 0.1 − 17.8 990 0 − 16.1 56,365 2.4 − 16.2
Multiple myeloma 2931 0.1 35.9 1680 0.1 19 95,563 4 20.3
Nasopharynx cancer 28,562 0.9 57.8 6079 0.2 − 41.9 362,911 12.1 − 40.6
Non-Hodgkin lymphoma 52,427 1.8 20.5 20,797 0.7 − 1.5 1,275,943 42.8 − 1.1
Other leukaemia 28,811 1 − 47.1 15,278 0.5 − 54.7 948,803 32 − 55.1
Other malignant neoplasms 141,110 4.8 28 51,453 1.7 2.3 3,230,198 109.1 3.3
Other pharynx cancer 7103 0.3 36.5 4360 0.2 21.6 244,994 10.4 21.8
Ovarian cancer 35,831 1.2 30.9 8896 0.3 12.8 529,030 17.6 13.8
Pancreatic cancer 9401 0.3 18.2 7609 0.3 16.2 420,797 13.9 16
Prostate cancer 5472 0.2 77.9 876 0 − 0.7 54,331 2.3 2.8
Stomach cancer 49,008 1.6 − 30.9 27,895 0.9 − 46.8 1,573,897 52 − 46.4
Testicular cancer 57,401 1.9 42 5352 0.2 − 3.9 349,083 11.7 − 0.6
Thyroid cancer 46,832 1.6 65.8 2853 0.1 − 0.6 190,923 6.4 4.7
Tracheal, bronchus, and lung cancer 32,601 1.1 − 24.1 24,772 0.8 − 29.4 1,386,001 45.8 − 29
Uterine cancer 19,415 0.8 14.9 1808 0.1 − 37.8 110,215 4.7 − 35
  1. Absolute incidence, deaths, and DALYs represent the total AYA cancer (35–39 years, both sexes combined) values. Rates are reported per 100,000 person-years. Uncertainty intervals are not reported because draw level data are not available for this customized age-group. DALY = disability-adjusted life-year. SDI = Socio-demographic Index