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Table 1 Burden of AYA cancers and percentage change in age-standardized rates from 1990 to 2019

From: The global, regional, and national burden of cancer among adolescents and young adults in 204 countries and territories, 1990–2019: a population-based study

 

Incidence

Deaths

DALYs

 

Number of incident cases, 2019

Age-standardized incidence rate (per 100,000 population), 2019

Percentage change in rates, 1990–2019

Number of deaths, 2019

Age-standardized death rate (per 100,000 population), 2019

Percentage change in rates, 1990–2019

Number of DALYs, 2019

Age-standardized DALYs rate (per 100,000 population), 2019

Percentage change in rates, 1990–2019

Global

1,194,382

39.7

10.7

396,117

13.2

− 21

23,491,284

782.3

− 20

Female

685,639

45.9

9.5

202,452

13.6

− 20.9

11,973,819

804.1

− 19.9

Male

508,743

33.5

12

193,665

12.8

− 21.2

11,517,464

760.4

− 20.2

High SDI

213,165

59.6

5.2

33,370

9.2

− 33.7

2,017,829

564.4

− 32

High-middle SDI

301,329

53.1

30.1

76,612

13.4

− 28.4

4,515,373

801.5

− 27

Middle SDI

355,636

36.9

16.5

131,819

13.7

− 25.4

7,783,143

810.2

− 24.1

Low-middle SDI

207,656

29.2

16.5

100,583

14.2

− 5.1

5,968,398

836.8

− 4.8

Low SDI

97,858

24.3

3.9

53,478

13.3

− 3.7

3,191,436

781.2

− 3.2

Acute lymphoid leukaemia

38,747

1.3

66.6

11,696

0.4

− 10.6

765,511

26.1

− 9.9

Acute myeloid leukaemia

20,183

0.7

5.6

12,166

0.4

− 0.1

747,561

25.2

− 0.2

Bladder cancer

14,095

0.5

29

2050

0.1

− 22.6

124,475

4.1

− 20.2

Brain and central nervous system cancer

61,511

2.1

23.9

29,105

1

− 6.9

1,746,906

58.4

− 6.6

Breast cancer

169,859

5.6

25.7

43,088

1.4

− 4.7

2,489,420

82.1

− 2.8

Cervical cancer

119,258

3.9

− 4.2

27,168

0.9

− 24.3

1,560,541

51.4

− 23.7

Chronic lymphoid leukaemia

4263

0.2

113.4

1010

0

1.7

61,375

2.6

4.3

Chronic myeloid leukaemia

9203

0.3

− 16

4956

0.2

− 33.1

294,861

9.8

− 33

Colon and rectum cancer

76,090

2.5

38.8

28,352

0.9

− 2.7

1,633,410

53.9

− 2.1

Esophageal cancer

8088

0.3

− 23.9

6215

0.3

− 29.7

343,752

14.5

− 29.4

Gallbladder and biliary tract cancer

3841

0.2

− 10.5

2390

0.1

− 17.1

132,562

5.6

− 17

Hodgkin lymphoma

33,388

1.1

− 8.6

8093

0.3

− 34.3

508,216

17.1

− 33.3

Kidney cancer

21,136

0.7

62.9

4017

0.1

20.7

239,153

7.9

22.1

Larynx cancer

4214

0.2

− 15.4

2250

0.1

− 29.3

128,189

5.4

− 28.7

Lip and oral cavity cancer

29,440

1

29.9

10,043

0.3

19.3

580,333

19.2

19.4

Liver cancer

25,430

0.8

− 50.9

18,573

0.6

− 57.5

1,046,876

34.6

− 57.1

Malignant skin melanoma

37,266

1.2

16.3

4248

0.1

− 23.9

259,089

8.6

− 21.6

Mesothelioma

1466

0.1

− 17.8

990

0

− 16.1

56,365

2.4

− 16.2

Multiple myeloma

2931

0.1

35.9

1680

0.1

19

95,563

4

20.3

Nasopharynx cancer

28,562

0.9

57.8

6079

0.2

− 41.9

362,911

12.1

− 40.6

Non-Hodgkin lymphoma

52,427

1.8

20.5

20,797

0.7

− 1.5

1,275,943

42.8

− 1.1

Other leukaemia

28,811

1

− 47.1

15,278

0.5

− 54.7

948,803

32

− 55.1

Other malignant neoplasms

141,110

4.8

28

51,453

1.7

2.3

3,230,198

109.1

3.3

Other pharynx cancer

7103

0.3

36.5

4360

0.2

21.6

244,994

10.4

21.8

Ovarian cancer

35,831

1.2

30.9

8896

0.3

12.8

529,030

17.6

13.8

Pancreatic cancer

9401

0.3

18.2

7609

0.3

16.2

420,797

13.9

16

Prostate cancer

5472

0.2

77.9

876

0

− 0.7

54,331

2.3

2.8

Stomach cancer

49,008

1.6

− 30.9

27,895

0.9

− 46.8

1,573,897

52

− 46.4

Testicular cancer

57,401

1.9

42

5352

0.2

− 3.9

349,083

11.7

− 0.6

Thyroid cancer

46,832

1.6

65.8

2853

0.1

− 0.6

190,923

6.4

4.7

Tracheal, bronchus, and lung cancer

32,601

1.1

− 24.1

24,772

0.8

− 29.4

1,386,001

45.8

− 29

Uterine cancer

19,415

0.8

14.9

1808

0.1

− 37.8

110,215

4.7

− 35

  1. Absolute incidence, deaths, and DALYs represent the total AYA cancer (35–39 years, both sexes combined) values. Rates are reported per 100,000 person-years. Uncertainty intervals are not reported because draw level data are not available for this customized age-group. DALY = disability-adjusted life-year. SDI = Socio-demographic Index