Fig. 4
From: Nanomaterials for cancer therapy: current progress and perspectives
Cancer treatment approaches based on nanomaterials. a Targeting cancer cells by passive targeting or active targeting. b Targeting TME including anti-angiogenesis, stromal cell and extracellular matrix. Bevacizumab was loaded in liposome and conjugated with VEGF to inhibit angiogenesis. HAase was modified onto NP surface and enhanced NP penetration ability. c IFN-γ as an immune modulator delivered by liposomes activated immune cells in cancer immunotherapy. HAase: hyaluronidase; IFN-γ: Cytokine Interferon gamma; NP: nanoparticle; TME: tumor microenvironment; VEGF: vascular endothelial growth factor