Fig. 2From: Antibody-drug conjugates for the treatment of lymphoma: clinical advances and latest progressADC mechanisms of action. Once bound to the corresponding cell-surface antigen of cancer cells, the ADC is internalized, and the cytotoxic payload is released, resulting in cell apoptosis. The drug can also diffuse into adjacent cells regardless of antigen positivity, resulting in cell death, termed “bystander killing”Back to article page