Fig. 1
Compartment reorganization during pancreatic cancer metastasis. a Cluster analysis of compartments according to PC1 values. b Left: Log2 (fold change) between primary cancer (PANC-1) and normal (HPNE) cells. Right: Log2 (fold change) between metastatic cancer (Capan-1) and normal (HPNE) cells (Wilcoxon rank-sum test, ****p < 0.0001). c GO enrichment for concordance genes located in B compartments of primary and normal cells but in A compartments of metastatic cancer cells. Whiskers of box plots are from Q1-1.5*IQR to Q3 + 1.5*IQR