Fig. 1From: Phase 1 study of M2698, a p70S6K/AKT dual inhibitor, in patients with advanced cancerPharmacodynamic effects of M2698 on pS6 in tumor tissue. Observed versus predicted relative change from baseline in pS6 levels in tumor tissue by dose (log-linear model). Observed data (n = 28) are represented by black dots and predicted data by a blue line and grey shaded area (95% confidence interval)Back to article page